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Immune Metabolic Regulation
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Research
Research Overview
Hepatic Metabolic Coordination
Immune Metabolic Regulation
Member
Professor
Current
Alumni
Publication
Selected
Entire
Communication
Gallery
Contact us
Contact us
ⓒ 고려대학교 생체대사분석공학 연구실
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14
2025
Binge drinking triggers VGLUT3-mediated glutamate secretion …
Journal name
Binge drinking triggers VGLUT3-mediated glutamate secretion and subsequent hepatic inflammation by activating mGluR5/NOX2 in Kupffer cells.
Author
Yang K, Kim K, Ryu T, Shim YR, Kim HH, Choi SE, Kim MJ, Chung KPS, Lee E, Lee KW, Jeon J, Kim P, Kim YS, Ku T, Jeong H, Nam KT, Lim G, Choi DW, Kim SH, Eun HS, Kim W, Jeong WI.
Journal+Date
Nature Communications. 2025 Jul.
Link
https://www.nature.com/articles/s41467-025-60820-3
13
2025
Metabolic Sparks in the Liver: Metabolic and Epigenetic Repr…
Journal name
Metabolic Sparks in the Liver: Metabolic and Epigenetic Reprogramming in Hepatic Stellate Cells Activation and Its Implications for Human Metabolic Diseases.
Author
Roh YJ*, Kim H*, Choi DW.
Journal+Date
Diabetes Metabolism Joural. 2025 May
Link
https://e-dmj.org/journal/view.php?doi=10.4093/dmj.2025.0195
12
2024
Unraveling the role of the mitochondrial one-carbon pathway …
Journal name
Unraveling the role of the mitochondrial one-carbon pathway in undifferentiated thyroid cancer by multi-omics analyses.
Journal name
Lee SE, Park S, Yi S, Choi NR, Lim MA, Chang JW, Won H, Kim JR, Ko HM, Chung E, Park YJ, Cho SW, Yu HW, Choi JY, Yeo M, Yi B, Yi K, Lim J, Koh J, Lee MJ, Heo JY, Yoon SJ, Kwon SW, Park J, Chu IS, Kim JM, Kim S, Shan Y, Liu L, Hong S, Choi DW, Park J, Ju YS, Shong M, Kim S, Koo BS and Kang YE.
Journal+Date
Nature Communications. 2024 Feb.
Link
https://www.nature.com/articles/s41467-024-45366-0
11
2023
Mitochondrial morphology controls fatty acid utilization by …
Journal name
Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl-CoA.
Author
Ngo J*, Choi DW*, Chen J, Shimir A, Stanley IA, Lako A, Ficarro S, Chapuy B, Rodig S, Shipp MA, Marto JA, Danial NN and Shirihai O.
Journal+Date
EMBO Journal. 2023 Mar.
Link
https://link.springer.com/article/10.15252/embj.2022111901
10
2022
The role of immunomodulatory metabolites in shaping the infl…
Journal name
The role of immunomodulatory metabolites in shaping the inflammatory response of macrophages.
Author
Park D*, Lim G*, Yoon SJ, Yi HS, and Choi DW.
Journal+Date
BMB Reports. 2022 Nov
Link
https://www.bmbreports.org/journal/view.html?volume=55&number=11&spage=519
9
2022
MsrB1-regulated GAPDH oxidation plays programmatic roles in …
Journal name
MsrB1-regulated GAPDH oxidation plays programmatic roles in shaping metabolic and inflammatory signatures during macrophage activation.
Author
Yoo HJ*, Choi DW#, Roh YJ, Kim S, Lee HM, Lim G, Park D, Shin D, Lee HJ, Lee BC, Kim J#.
Journal+Date
Cell Reports. 2022 Nov
Link
https://www.sciencedirect.com/science/article/pii/S2211124722014632
8
2022
MCL-1 is a Master Regulator of Cancer Dependency on Fatty Ac…
Journal name
MCL-1 is a Master Regulator of Cancer Dependency on Fatty Acid Oxidation.
Author
Prew M, Adhikary U, Choi DW, Paulo J, Budhraja A, Opferman J, Gygi S, Danial NN, and Walensky L.
Journal+Date
Cell Reports. 2022 Oct.
Link
https://www.sciencedirect.com/science/article/pii/S2211124722012864?via%3Dihub
7
2013-2020
Glucose dependent partitioning of arginine to the urea cycle…
Journal name
Glucose dependent partitioning of arginine to the urea cycle protects b-cell from inflammation.
Author
Fu A, Alvarez-Perez JC, Avizonis D, Kin T, Ficarro S, Choi DW, Karakose E, Badur M, Evans L, Rosselot C, Bridon G , Bird G, Seo H, Dhe-Paganon S, Kamphorst J, Stewart A, Shapiro J, Marto JA, Walensky L, Jones R, Garcia-Ocana A, Danial NN.
Journal+Date
Nature Metabolism. 2020 May
Link
https://www.nature.com/articles/s42255-020-0199-4
6
2013-2020
HCF-1 regulates de novo lipogenesis through a nutrient sensi…
Journal name
HCF-1 regulates de novo lipogenesis through a nutrient sensitive complex with ChREBP.
Author
Lane EA*, Choi DW*, Garcia-Haro L, Levine ZG, Tedoldi M, Walker S and Danial NN.
Journal+Date
Molecular Cell. 2019 Jul
Link
https://www.sciencedirect.com/science/article/pii/S1097276519303910?via%3Dihub
5
2013-2020
The deubuiquitinating enzyme USP20 stabilize ULK1 and promot…
Journal name
The deubuiquitinating enzyme USP20 stabilize ULK1 and promotes autophagy initiation.
Author
Kim JH*, Seo D*, Kim SJ*, Choi DW*, Park JS, Ha J, Jung SM, Seo KW, Lee EW, Lee YS, Cheong H, Choi CY and Park SH.
Journal+Date
EMBO reports. 2018 Apr
Link
https://link.springer.com/article/10.15252/embr.201744378
4
2013-2020
Differential contribution of the mitochondrial translation p…
Journal name
Differential contribution of the mitochondrial translation pathway to the survival of diffuse large B-cell lymphoma subsets.
Author
Norberg E, Lako A, Chen P, Stanley IA, Zhou F, Ficarro S, Chapuy B, Chen L, Rodig S, Shin D, Choi DW, Lee S, Shipp MA, Marto JA and Danial NN.
Journal+Date
Cell Death and Differentiation. 2017 Feb
Link
https://www.nature.com/articles/cdd2016116
3
2013-2020
HIPK2 tumor suppressor regulates tumor cell growth via the p…
Journal name
HIPK2 tumor suppressor regulates tumor cell growth via the phosphorylation of Notch1.
Author
Ann E, Kim M, Yoon J, Ahn J, Jo E, Lee H, Lee H, Kang H, Choi DW, Chun K, Lee JS, Choi CY, Ferrando A, and Park H.
Journal+Date
Cancer Research. 2016 Aug.
Link
https://aacrjournals.org/cancerres/article/76/16/4728/544281/Tumor-Suppressor-HIPK2-Regulates-Malignant-Growth?guestAccessKey=
2
2013-2020
WSB1 promotes tumor metastasis by inducing pVHL degradation.
Journal name
WSB1 promotes tumor metastasis by inducing pVHL degradation.
Author
Kim JJ, Lee SB, Jang J, Yi S, Kim S, Han S, Lee J, Tong S, Gao B, Evans D, Choi DW, Bo Qin, Liu T, Zhang H, Deng M, Jen J, Zhang J, Wang L, and Lou Z.
Journal+Date
Genes & Development. 2015 Nov
Link
https://genesdev.cshlp.org/content/29/21/2244.long
1
2013-2020
A Homeostatic Regulator of the DNA Damage Response, Is Targe…
Journal name
A Homeostatic Regulator of the DNA Damage Response, Is Targeted by HIPK2 for Phosphorylation and Degradation.
Author
Choi DW*, Na W*, Kabir MH, Yi E, Kwon S, Yeom J, Ahn JW, Choi HH, Lee Y, Seo KW, Shin MK, Park SH, Yoo HY, Isono KI, Koseki H, Kim ST, Lee C, Kwon YK, Choi CY. WIP1,
Journal+Date
Molecular Cell. 2013 July
Link
https://www.cell.com/molecular-cell/fulltext/S1097-2765(13)00447-4